Polyethersulfone Membrane Cartridge, 0.65 Micron Rating, BPS-60, Biological Grade
Biopharmaceutical grade PS filters are hydrophilic and manufactured with asymmetric polyethersulfone (PES) membrane. PES membrane exhibits excellent flow rates with high throughput. BPS cartridge filters are use for critical bioburden reduction applications in the biopharmaceutical industry. Specific applications for BPS filters are bacteria removal in buffers, USP Water for Injection (WFI), SVPs, LVPs and other biopharmaceutical products. The filter elements are 100% integrity tested during production.
Polyethersulfone is particularly suited for the filtration of products that contain elements that adsorb to the media, such as preservatives and proteins. The lower binding characteristics of polyethersulfone make it a good choice for filtration of valuable protein solutions such as vaccines and biologicals.
Maximum Operating Parameters
• Micron Rating: 0.65 Micron
• Maximum Operating Temperature*: 180°F (82°C) at 10 psid in water
• Forward Differential Pressure: 50 psi (3.4 bar) at 20°C
• Reverse Differential Pressure: 40 psi (2.7 bar) at 20°C
• Recommended Changeout Pressure: 35 psid (2.4 psid)
Dimensions (Cylindrical)
• Length: 5 to 40" (12.7 101.6 cm) nominal
• Outside Diameter: 2.75" (7.0 cm) nominal
• Surface Area: 7.0 ft2 (0.65 m2) Per 10" length
Applications
Final Filtration of:
Maximum Operating Parameters
• Micron Rating: 0.65 Micron
• Maximum Operating Temperature*: 180°F (82°C) at 10 psid in water
• Forward Differential Pressure: 50 psi (3.4 bar) at 20°C
• Reverse Differential Pressure: 40 psi (2.7 bar) at 20°C
• Recommended Changeout Pressure: 35 psid (2.4 psid)
Construction Materials
• Filtration Media: Dual Layered Polyethersulfone (PES) Membrane
• Filtration Media Support: Polypropylene
• End Caps: Polypropylene
• Center Core: Polypropylene
• Outer Support Cage: Polypropylene
• Filtration Media: Dual Layered Polyethersulfone (PES) Membrane
• Filtration Media Support: Polypropylene
• End Caps: Polypropylene
• Center Core: Polypropylene
• Outer Support Cage: Polypropylene
• Sealing Method: Thermal Bonding
• Length: 5 to 40" (12.7 101.6 cm) nominal
• Outside Diameter: 2.75" (7.0 cm) nominal
• Surface Area: 7.0 ft2 (0.65 m2) Per 10" length
Applications
Final Filtration of:
• Buffers and Feedstocks • Vaccines
• WFI Water • SVPs
• Solvents • LVPs
Validation
BPS grade cartridges are validated using test procedures that comply with the intent of both ASTM F 838-05 and HIMA protocols for the determination of bacterial retention in filters used for liquid filtration. (0.22 um challenged with Brevundimonas diminutal) (0.45 um challenged with Serratia marscecens) (0.65 um challenged with Saccharomyces cerevisiae). Validation guide is available for 0.22 micron to meet regulatory requirements.
BPS grade cartridges are validated using test procedures that comply with the intent of both ASTM F 838-05 and HIMA protocols for the determination of bacterial retention in filters used for liquid filtration. (0.22 um challenged with Brevundimonas diminutal) (0.45 um challenged with Serratia marscecens) (0.65 um challenged with Saccharomyces cerevisiae). Validation guide is available for 0.22 micron to meet regulatory requirements.
